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03/26/2005:

"Family Wonders if Prozac Prompted School Shootings"

RED LAKE, Minn., March 25 - In their sleepless search for answers, the family of Jeff Weise, the teenager who killed nine people and then himself, says it is left wondering about the drugs he was prescribed for his waves of depression.

On Friday, as Tammy Lussier prepared to bury Mr. Weise, who was her nephew, and her father, who was among those he killed, she found herself looking back over the last year, she said, when Mr. Weise began taking the antidepressant Prozac after a suicide attempt that Ms. Lussier described as a "cry for help."

"They kept upping the dose for him," she said, "and by the end, he was taking three of the 20 milligram pills a day. I can't help but think it was too much, that it must have set him off."

Lee Cook, another relative of Mr. Weise, said his medication had increased a few weeks before the shootings on Monday.

"I do wonder," Mr. Cook said, "whether on top of everything else he had going on in his life, on top of all the other problems, whether the drugs could have been the final straw."

The effects of antidepressants on young people remain a topic of fierce debate among scientists and doctors.

Last year, a federal panel of drug experts said antidepressants could cause children and teenagers to become suicidal. The Food and Drug Administration has since required the makers of antidepressants to warn of that danger on their labels for the medications.

The suicide risk is particularly acute when therapy starts or a dosage changes, the drug agency has warned.
Full Article: nytimes.com